Primary reconstruction with titanium mesh in comminuted and open skull fracture: long-term follow-up to verify its feasibility

doi:10.3969/j.issn.2095-4344.2014.43.021

Abstract

Abstract:

BACKGROUND: At present, scholars generally believe that the physical and chemical properties of titanium mesh are fine as easy plastic, easy cutting, good corrosion resistance and wear resistance, non-magnetic, less effect on CT or MRI results, good histocompatibility and resistance to stress. The titanium mesh is regarded as an ideal material for cranioplasty.
OBJECTIVE: To explore the clinical feasibility of primary reconstruction of comminuted and open skull fracture with titanium mesh.
METHODS: Sixty-two cases of comminuted and open skull fracture were analyzed retrospectively, including 49 males and 13 females, aged 7-69 years. Among these 62 patients, 30 patients underwent debridement and then after 6-12 months, they received titanium mesh reconstruction, serving as control group. Another 32 cases underwent debridement and titanium mesh reconstruction in the same time as observation group. All the cases were followed-up for 1-2 years to observe wound healing, complications and hospitalization cost.
RESULTS AND CONCLUSION: During the follow-up, no wound infection and intracranial infection occurred in the two groups. The incidence of intracranial hematoma, epilepsy, and other complications was higher in the control group than the observation group (P < 0.05), and the hospitalization cost was also higher in the control
group than the observation group (P < 0.05). These findings indicate that primary reconstruction with titanium mesh is feasible in the treatment of comminuted and open skull fracture and can significantly reduce the incidence of complications and hospitalization costs.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

全文链接：

Key words: skull fractures, postoperative complications, fractures, open

CLC Number:

R318

Zhang Xiang, Wang Zeng-liang, Chen Dan-li, Wu Gan-chun, Xu Dan-shu, Wang Yong-xin . Primary reconstruction with titanium mesh in comminuted and open skull fracture: long-term follow-up to verify its feasibility[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(43): 7012-7017.

Figures/Tables 2

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